The Center for Dynamical Biomarkers (DBIOM) at Beth Israel Deaconess Medical Center, a major teaching hospital of Harvard Medical School, is focusing on fundamental theory and novel computational algorithms for characterizing physiological states in terms of their dynamical properties. These Dynamical Biomarkers may provide more sensitive and accurate assessments of physiological states than conventional biomarkers.  

 

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Recent Publications

Dynamic Brain-Body Coupling of Breath-by-Breath O2-CO2 Exchange Ratio with Resting State Cerebral Hemodynamic Fluctuations
Andrew C Ahn
Effects of different mattresses on sleep quality in healthy subjects: An ECG-based study
CK Peng, Yan Ma, Brian Gow
Cerebrovascular reactivity assessment with O2-CO2 exchange ratio under brief breath hold challenge
Andrew C Ahn
Detecting causality in multivariate time series via non-uniform embedding
Yan Ma
Heart rate variability and surgical pleth index under anesthesia in poor and normal sleepers
Albert C Yang
The application of multiscale joint permutation entropy on multichannel sleep electroencephalography
Yan Ma, CK Peng
Heart Rate Dynamics in Patients with Obstructive Sleep Apnea: Heart Rate Variability and Entropy
Yan Ma
Validating the Enlarged Kyd Canon: a New Approach
Albert C Yang
Diagram building system and method for a signal data decomposition and analysis
CK Peng
Heart Rhythm Complexity Impairment in Patients with Pulmonary Hypertension
CK Peng